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PROKR1 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q8TCW9 |
| Reactivity | Human, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 45kDa |
| Dilution | IHC-P (13 µg/ml) |
| Gene ID | 10887 |
|---|---|
| Other Names | Prokineticin receptor 1, PK-R1, G-protein coupled receptor 73, G-protein coupled receptor ZAQ, GPR73a, PROKR1, GPR73, PKR1 |
| Target/Specificity | Human PROKR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PROKR2 (68%). |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | PROKR1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PROKR1 |
|---|---|
| Synonyms | GPR73, PKR1 |
| Function | Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Location | Localizes to glandular epithelium, stroma and vascular endothelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non- pregnant endometrium. Expressed in the stomach, throughout the small intestine, colon, rectum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary, brain, spleen, prostate and pancreas. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy.
References
Masuda Y.,et al.Biochem. Biophys. Res. Commun. 293:396-402(2002).
Soga T.,et al.Biochim. Biophys. Acta 1579:173-179(2002).
Lin D.C.-H.,et al.J. Biol. Chem. 277:19276-19280(2002).
Hillier L.W.,et al.Nature 434:724-731(2005).
Martin A.L.,et al.Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
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