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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PROKR1 Antibody (C-Terminus)   

PROKR1 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - PROKR1 Antibody (C-Terminus) ALS10628
    Anti-PROKR1 antibody ALS10628 IHC of human colon.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q8TCW9
Reactivity Human, Monkey
Host Rabbit
Clonality Polyclonal
Calculated MW 45kDa
Dilution IHC-P (13 µg/ml)
Additional Information
Gene ID 10887
Other Names Prokineticin receptor 1, PK-R1, G-protein coupled receptor 73, G-protein coupled receptor ZAQ, GPR73a, PROKR1, GPR73, PKR1
Target/Specificity Human PROKR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PROKR2 (68%).
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsPROKR1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PROKR1
Synonyms GPR73, PKR1
Function Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Localizes to glandular epithelium, stroma and vascular endothelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the stomach, throughout the small intestine, colon, rectum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary, brain, spleen, prostate and pancreas.
Volume 50 µl
Research Areas
Citations (0)

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Background

Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy.

References

Masuda Y.,et al.Biochem. Biophys. Res. Commun. 293:396-402(2002).
Soga T.,et al.Biochim. Biophys. Acta 1579:173-179(2002).
Lin D.C.-H.,et al.J. Biol. Chem. 277:19276-19280(2002).
Hillier L.W.,et al.Nature 434:724-731(2005).
Martin A.L.,et al.Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS10628
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