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CRHR2 / CRF2 Receptor Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - CRHR2 / CRF2 Receptor Antibody (N-Terminus) ALS10681
    Anti-CRHR2 antibody ALS10681 IHC of human brain, pituitary.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q13324
Reactivity Human, Rabbit, Monkey, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 48kDa
Dilution IHC-P (8 µg/ml)
Additional Information
Gene ID 1395
Other Names Corticotropin-releasing factor receptor 2, CRF-R-2, CRF-R2, CRFR-2, Corticotropin-releasing hormone receptor 2, CRH-R-2, CRH-R2, CRHR2, CRF2R, CRH2R
Target/Specificity Human CRHR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsCRHR2 / CRF2 Receptor Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRHR2
Synonyms CRF2R, CRH2R
Function G-protein coupled receptor for CRH (corticotropin- releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
Cellular Location Cell membrane; Multi-pass membrane protein
Volume 50 µl
Research Areas
Citations (0)

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Background

G-protein coupled receptor for CRH (corticotropin- releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.

References

Liaw C.W.,et al.Endocrinology 137:72-77(1996).
Kostich W.A.,et al.Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases.
Kostich W.A.,et al.Mol. Endocrinol. 12:1077-1085(1998).
Suwa M.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
King M.M.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS10681
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