|Dilution||IHC-P (15-30 µg/ml)|
|Other Names||Probable G-protein coupled receptor 97, G-protein coupled receptor PGR26, GPR97, PGR26|
|Target/Specificity||Human GPR97. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||ADGRG3 / GPR97 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Orphan receptor that regulates migration of lymphatic endothelial cells in vitro via the small GTPases RhoA and CDC42 (PubMed:24178298). Regulates B-cell development (By similarity). Seems to signal through G-alpha(q)-proteins (PubMed:22575658).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in cultured primary dermal lymphatic endothelial cells.|
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Provided below are standard protocols that you may find useful for product applications.
Okaze H.,et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
Fredriksson R.,et al.FEBS Lett. 531:407-414(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
Vassilatis D.K.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:4903-4908(2003).
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