ADGRG3 / GPR97 Antibody (Extracellular Domain)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | Q86Y34 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 61kDa |
Dilution | IHC-P (15-30 µg/ml) |
Gene ID | 222487 |
---|---|
Other Names | Probable G-protein coupled receptor 97, G-protein coupled receptor PGR26, GPR97, PGR26 |
Target/Specificity | Human GPR97. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | ADGRG3 / GPR97 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ADGRG3 (HGNC:13728) |
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Synonyms | GPR97, PGR26 |
Function | Orphan receptor that regulates migration of lymphatic endothelial cells in vitro via the small GTPases RhoA and CDC42 (PubMed:24178298). Regulates B-cell development (By similarity). Seems to signal through G-alpha(q)-proteins (PubMed:22575658). |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Expressed in cultured primary dermal lymphatic endothelial cells. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Orphan receptor.
References
Okaze H.,et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
Fredriksson R.,et al.FEBS Lett. 531:407-414(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
Vassilatis D.K.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:4903-4908(2003).
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