|Reactivity||Human, Monkey, Bovine|
|Dilution||IHC-P (2-3 µg/ml)|
|Other Names||Prostaglandin E2 receptor EP4 subtype, PGE receptor EP4 subtype, PGE2 receptor EP4 subtype, Prostanoid EP4 receptor, PTGER4, PTGER2|
|Target/Specificity||Human PTGER4 / EP4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||PTGER4 / EP4 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle|
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Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
Bastien L.,et al.J. Biol. Chem. 269:11873-11877(1994).
An S.,et al.Biochem. Biophys. Res. Commun. 197:263-270(1993).
Foord S.M.,et al.Genomics 35:182-188(1996).
Mori K.,et al.J. Mol. Med. 74:333-336(1996).
Kopatz S.A.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
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