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PTGER4 / EP4 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - PTGER4 / EP4 Antibody (C-Terminus) ALS10712
    Human, Colon: Formalin-Fixed Paraffin-Embedded (FFPE)
  • ICC - PTGER4 / EP4 Antibody (C-Terminus) ALS10712
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, ICC
Primary Accession P35408
Reactivity Human, Monkey
Host Rabbit
Clonality Polyclonal
Calculated MW 53kDa
Dilution IHC-P (4-15 µg/ml)
Additional Information
Gene ID 5734
Other Names Prostaglandin E2 receptor EP4 subtype, PGE receptor EP4 subtype, PGE2 receptor EP4 subtype, Prostanoid EP4 receptor, PTGER4, PTGER2
Target/Specificity Human PTGER4 / EP4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsPTGER4 / EP4 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTGER4
Synonyms PTGER2
Function Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle
Volume 50 µl
Research Areas
Citations (0)

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Background

Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

References

Bastien L.,et al.J. Biol. Chem. 269:11873-11877(1994).
An S.,et al.Biochem. Biophys. Res. Commun. 197:263-270(1993).
Foord S.M.,et al.Genomics 35:182-188(1996).
Mori K.,et al.J. Mol. Med. 74:333-336(1996).
Kopatz S.A.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS10712
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