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EDNRA / Endothelin A Receptor Antibody (Extracellular Domain)

Rabbit Polyclonal Antibody

  • IHC - EDNRA / Endothelin A Receptor Antibody (Extracellular Domain) ALS10726
    Anti-Endothelin A Receptor antibody ALS10726 IHC of human heart.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P25101
Reactivity Human, Monkey
Host Rabbit
Clonality Polyclonal
Calculated MW 49kDa
Dilution IHC-P (3-16 µg/ml)
Additional Information
Gene ID 1909
Other Names Endothelin-1 receptor, Endothelin A receptor, ET-A, ETA-R, hET-AR, EDNRA, ETA, ETRA
Target/Specificity Human Endothelin A Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except EDNRB (72%).
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsEDNRA / Endothelin A Receptor Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ETA, ETRA
Function Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and liver but no expression in umbilical vein endothelial cells. Within the placenta, isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in the villi and stem villi vessels.
Volume 50 µl
Research Areas
Citations (0)

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Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.


Adachi M.,et al.Biochem. Biophys. Res. Commun. 180:1265-1272(1991).
Cyr C.,et al.Biochem. Biophys. Res. Commun. 181:184-190(1991).
Hosoda K.,et al.FEBS Lett. 287:23-26(1991).
Arai H.,et al.Jpn. Circ. J. 56:1303-1307(1992).
Elshourbagy N.A.,et al.J. Biol. Chem. 268:3873-3879(1993).

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$ 395.00
Cat# ALS10726
(40 western blots)
Availability: 5 days
Bulk Size
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