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RAIG2 / GPRC5B Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - RAIG2 / GPRC5B Antibody (N-Terminus) ALS10730
    Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q9NZH0
Reactivity Human, Mouse, Rabbit, Monkey, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 45kDa
Dilution IHC-P (5-10 µg/ml)
Additional Information
Gene ID 51704
Other Names G-protein coupled receptor family C group 5 member B, A-69G12.1, Retinoic acid-induced gene 2 protein, RAIG-2, GPRC5B, RAIG2
Target/Specificity Human GPRC5B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsRAIG2 / GPRC5B Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPRC5B
Synonyms RAIG2
Function Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
Cellular Location Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Localized in the plasma membrane and perinuclear vesicles
Tissue Location Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte. According to PubMed:10945465, highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal cord as well as in dorsal root ganglia (DRG). In the periphery, expression levels are relatively low, compared to the CNS, with the strongest expression detected in pancreas, testis, uterus, and stomach
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.

References

Braeuner-Osborne H.,et al.Genomics 65:121-128(2000).
Robbins M.J.,et al.Genomics 67:8-18(2000).
Wei H.,et al.Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
Cool B.H.,et al.Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 467.50
Cat# ALS10730
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