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TACR3 / NK3R Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - TACR3 / NK3R Antibody (C-Terminus) ALS10739
    Anti-TACR3 antibody ALS10739 IHC of human brain, hippocampus.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P29371
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 52kDa
Dilution IHC-P (20 µg/ml)
Additional Information
Gene ID 6870
Other Names Neuromedin-K receptor, NKR, NK-3 receptor, NK-3R, Neurokinin B receptor, Tachykinin receptor 3, TACR3, NK3R, TAC3R
Target/Specificity Human TACR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsTACR3 / NK3R Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TACR3
Synonyms NK3R, TAC3R
Function This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.
Cellular Location Cell membrane; Multi-pass membrane protein.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.

References

Huang R.-R.C.,et al.Biochem. Biophys. Res. Commun. 184:966-972(1992).
Buell G.,et al.FEBS Lett. 299:90-95(1992).
Takahashi K.,et al.Eur. J. Biochem. 204:1025-1033(1992).
Kopatz S.A.,et al.Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
Topaloglu A.K.,et al.Nat. Genet. 41:354-358(2009).

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$ 467.50
Cat# ALS10739
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