|Dilution||IHC-P (20-40 µg/ml)|
|Other Names||Beta-3 adrenergic receptor, Beta-3 adrenoreceptor, Beta-3 adrenoceptor, ADRB3, ADRB3R, B3AR|
|Target/Specificity||Human ADRB3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except OR2G3 (44%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||ADRB3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed mainly in adipose tissues.|
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Provided below are standard protocols that you may find useful for product applications.
Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
Emorine L.J.,et al.Science 245:1118-1121(1989).
van Spronsen A.,et al.Eur. J. Biochem. 213:1117-1124(1993).
Lelias J.M.,et al.FEBS Lett. 324:127-130(1993).
Kopatz S.A.,et al.Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
Granneman J.G.,et al.Mol. Pharmacol. 42:964-970(1992).
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