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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   GPCR Antibodies   >   RXFP2 / LGR8 Antibody (Cytoplasmic Domain)   

RXFP2 / LGR8 Antibody (Cytoplasmic Domain)

Rabbit Polyclonal Antibody

     
  • IHC - RXFP2 / LGR8 Antibody (Cytoplasmic Domain) ALS10780
    Anti-RXFP2 / LGR8 antibody IHC of human Brain, Glioblastoma.
  • IHC - RXFP2 / LGR8 Antibody (Cytoplasmic Domain) ALS10780
    Anti-RXFP2 / LGR8 antibody IHC of human Breast, Carcinoma.
  • IHC - RXFP2 / LGR8 Antibody (Cytoplasmic Domain) ALS10780
    Anti-RXFP2 antibody ALS10780 IHC of human uterus.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q8WXD0
Reactivity Human, Horse
Host Rabbit
Clonality Polyclonal
Calculated MW 86kDa
Dilution IHC-P (26-130 µg/ml)
Additional Information
Gene ID 122042
Other Names Relaxin receptor 2, G-protein coupled receptor 106, G-protein coupled receptor affecting testicular descent, Leucine-rich repeat-containing G-protein coupled receptor 8, Relaxin family peptide receptor 2, RXFP2, GPR106, GREAT, LGR8
Target/Specificity Human RXFP2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsRXFP2 / LGR8 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RXFP2
Synonyms GPR106, GREAT, LGR8
Function Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed mainly in the brain, kidney, muscle, testis, thyroid, uterus, peripheral blood cells and bone marrow
Volume 50 µl
Research Areas
Citations (0)

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Background

Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).

References

Hsu S.Y.,et al.Science 295:671-674(2002).
Gorlov I.P.,et al.Hum. Mol. Genet. 11:2309-2318(2002).
Muda M.,et al.Mol. Hum. Reprod. 11:591-600(2005).
Dunham A.,et al.Nature 428:522-528(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS10780
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