|Dilution||IHC-P (21 µg/ml)|
|Other Names||Mas-related G-protein coupled receptor member X3, Sensory neuron-specific G-protein coupled receptor 1/2, MRGPRX3, MRGX3, SNSR1, SNSR2|
|Target/Specificity||Human MRGPRX3 / MRGX3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MRGPRX4 (59%), LRRK2 (53%), CACNB4 (47%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||MRGPRX3 / MRGX3 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||MRGX3, SNSR1, SNSR2|
|Function||Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons|
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Provided below are standard protocols that you may find useful for product applications.
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).
Dong X.,et al.Cell 106:619-632(2001).
Lembo P.M.C.,et al.Nat. Neurosci. 5:201-209(2002).
Martin A.L.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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