MRGPRX3 / MRGX3 Antibody (Extracellular Domain)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | Q96LB0 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 36kDa |
Dilution | IHC-P (21 µg/ml) |
Gene ID | 117195 |
---|---|
Other Names | Mas-related G-protein coupled receptor member X3, Sensory neuron-specific G-protein coupled receptor 1/2, MRGPRX3, MRGX3, SNSR1, SNSR2 |
Target/Specificity | Human MRGPRX3 / MRGX3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MRGPRX4 (59%), LRRK2 (53%), CACNB4 (47%). |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | MRGPRX3 / MRGX3 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MRGPRX3 |
---|---|
Synonyms | MRGX3, SNSR1, SNSR2 |
Function | Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).
References
Dong X.,et al.Cell 106:619-632(2001).
Lembo P.M.C.,et al.Nat. Neurosci. 5:201-209(2002).
Martin A.L.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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