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MRGPRX3 / MRGX3 Antibody (Extracellular Domain)

Rabbit Polyclonal Antibody

     
  • IHC - MRGPRX3 / MRGX3 Antibody (Extracellular Domain) ALS10811
    Anti-MRGPRX3 / MRGX3 antibody IHC of human brain, cerebellum, Purkinje neurons.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q96LB0
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 36kDa
Dilution IHC-P (21 µg/ml)
Additional Information
Gene ID 117195
Other Names Mas-related G-protein coupled receptor member X3, Sensory neuron-specific G-protein coupled receptor 1/2, MRGPRX3, MRGX3, SNSR1, SNSR2
Target/Specificity Human MRGPRX3 / MRGX3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MRGPRX4 (59%), LRRK2 (53%), CACNB4 (47%).
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsMRGPRX3 / MRGX3 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MRGPRX3
Synonyms MRGX3, SNSR1, SNSR2
Function Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons
Volume 50 µl
Research Areas
Citations (0)

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Background

Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).

References

Dong X.,et al.Cell 106:619-632(2001).
Lembo P.M.C.,et al.Nat. Neurosci. 5:201-209(2002).
Martin A.L.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS10811
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