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NR0B1 / DAX1 Antibody (Ligand-binding Domain)

Rabbit Polyclonal Antibody

     
  • IHC - NR0B1 / DAX1 Antibody (Ligand-binding Domain) ALS10830
    Anti-DAX1 antibody ALS10830 IHC of human testis.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P51843
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 52kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 190
Other Names Nuclear receptor subfamily 0 group B member 1, DSS-AHC critical region on the X chromosome protein 1, Nuclear receptor DAX-1, NR0B1, AHC, DAX1
Target/Specificity Human DAX1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsNR0B1 / DAX1 Antibody (Ligand-binding Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NR0B1
Synonyms AHC, DAX1
Function Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity).
Cellular Location Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and nucleus. Homodimers exits in the cytoplasm and in the nucleus
Volume 50 µl
Research Areas
Citations (0)

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Background

Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity).

References

Zanaria E.,et al.Nature 372:635-641(1994).
Guo W.,et al.J. Clin. Endocrinol. Metab. 81:2481-2486(1996).
Altincicek B.,et al.J. Biol. Chem. 275:7662-7667(2000).
Suzuki T.,et al.Mol. Cell. Biol. 23:238-249(2003).
Ho J.,et al.Mol. Genet. Metab. 83:330-336(2004).

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$ 395.00
Cat# ALS10830
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