|Reactivity||Human, Mouse, Rabbit, Hamster, Monkey, Pig, Chicken, Horse, Bovine, Dog|
|Dilution||IHC-P (4 µg/ml)|
|Other Names||Nuclear receptor subfamily 6 group A member 1, Germ cell nuclear factor, GCNF, hGCNF, Retinoid receptor-related testis-specific receptor, RTR, hRTR, NR6A1, GCNF|
|Target/Specificity||Human NR6A1 / GCNF. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||NR6A1 / GCNF Antibody (Ligand-binding Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis (By similarity).|
|Tissue Location||Shows highest expression in the germ cells of the adult testis.|
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Provided below are standard protocols that you may find useful for product applications.
Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis (By similarity).
Suesens U.,et al.Biochim. Biophys. Acta 1309:179-182(1996).
Kapelle M.,et al.Biochim. Biophys. Acta 1352:13-17(1997).
Lei W.,et al.J. Mol. Endocrinol. 18:167-176(1997).
Agoulnik I.Y.,et al.FEBS Lett. 424:73-78(1998).
Schneider-Hirsch S.,et al.J. Recept. Signal Transduct. 18:1-13(1998).
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