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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ADGRE2 / EMR2 Antibody (N-Terminus)   

ADGRE2 / EMR2 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - ADGRE2 / EMR2 Antibody (N-Terminus) ALS10835
    Anti-EMR2 antibody ALS10835 IHC of human lung, neutrophils.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q9UHX3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 90kDa
Dilution IHC-P (12 µg/ml)
Additional Information
Gene ID 30817
Other Names EGF-like module-containing mucin-like hormone receptor-like 2, EGF-like module receptor 2, CD312, EMR2
Target/Specificity Human EMR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsADGRE2 / EMR2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EMR2
Function Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell projection, ruffle membrane; Multi-pass membrane protein Note=Localized at the leading edge of migrating cells
Tissue Location Expression is restricted to myeloid cells. Highest expression was found in peripheral blood leukocytes, followed by spleen and lymph nodes, with intermediate to low levels in thymus, bone marrow, fetal liver, placenta, and lung, and no expression in heart, brain, skeletal muscle, kidney, or pancreas. Expression is also detected in monocyte/macrophage and Jurkat cell lines but not in other cell lines tested
Volume 50 µl
Research Areas
Citations (0)

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Background

Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF.

References

Lin H.-H.,et al.Genomics 67:188-200(2000).
Suwa M.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).
Chang G.-W.,et al.FEBS Lett. 547:145-150(2003).

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$ 395.00
Cat# ALS10835
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