|Application ||IHC-P, E|
|Dilution||IHC-P (2.5 µg/ml)|
|Other Names||EGF-like module-containing mucin-like hormone receptor-like 3, EGF-like module receptor 3, EGF-like module-containing mucin-like hormone receptor-like 3 subunit alpha, EGF-like module-containing mucin-like hormone receptor-like 3 subunit beta, EMR3|
|Target/Specificity||Human EMR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||ADGRE3 / EMR3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Orphan receptor that may play a role myeloid-myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of monocytes-derived macrophages and activated neutrophils.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Displays a predominantly leukocyte-restricted expression, with highest levels in neutrophils, monocytes and macrophages.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor probably involved in myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of momocytes- derived macrophages and activated neutrophils.
Stacey M.,et al.J. Biol. Chem. 276:18863-18870(2001).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Grimwood J.,et al.Nature 428:529-535(2004).
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