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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SGK2 Antibody (Kinase Domain)   

SGK2 Antibody (Kinase Domain)

Rabbit Polyclonal Antibody

     
  • IHC - SGK2 Antibody (Kinase Domain) ALS10893
    Anti-SGK2 antibody ALS10893 IHC of human kidney.
  • IHC - SGK2 Antibody (Kinase Domain) ALS10893
    Anti-SGK2 antibody ALS10893 IHC of human pancreas.
  • IHC - SGK2 Antibody (Kinase Domain) ALS10893
    Anti-SGK2 antibody IHC of human Lung, Non-Small Cell Carcinoma.
  • IHC - SGK2 Antibody (Kinase Domain) ALS10893
    Anti-SGK2 antibody IHC of human Brain, Glioblastoma.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q9HBY8
Reactivity Human, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 48kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 10110
Other Names Serine/threonine-protein kinase Sgk2, 2.7.11.1, Serum/glucocorticoid-regulated kinase 2, SGK2
Target/Specificity Human SGK2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SGK3 (67%).
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsSGK2 Antibody (Kinase Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SGK2
Function Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up- regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase.
Cellular Location Cytoplasm. Nucleus
Tissue Location Highly expressed in liver, kidney and pancreas, and at lower levels in brain
Research Areas
Citations (0)

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Background

Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up- regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase.

References

Kobayashi T.,et al.Biochem. J. 344:189-197(1999).
Li H.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Deloukas P.,et al.Nature 414:865-871(2001).
Henke G.,et al.Kidney Blood Press. Res. 25:370-374(2002).

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$ 395.00
Cat# ALS10893
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