SGK2 Antibody (Internal)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | Q9HBY8 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 48kDa |
Dilution | IHC-P (7 µg/ml) |
Gene ID | 10110 |
---|---|
Other Names | Serine/threonine-protein kinase Sgk2, 2.7.11.1, Serum/glucocorticoid-regulated kinase 2, SGK2 |
Target/Specificity | Human SGK2. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | SGK2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SGK2 |
---|---|
Function | Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up-regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase. |
Cellular Location | Cytoplasm. Nucleus |
Tissue Location | Highly expressed in liver, kidney and pancreas, and at lower levels in brain. |
Volume | 50 µl |
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Background
Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up- regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase.
References
Kobayashi T.,et al.Biochem. J. 344:189-197(1999).
Li H.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Deloukas P.,et al.Nature 414:865-871(2001).
Henke G.,et al.Kidney Blood Press. Res. 25:370-374(2002).
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