|Reactivity||Human, Rabbit, Monkey, Horse, Bovine|
|Dilution||IHC-P (4 µg/ml)|
|Other Names||Dual specificity protein phosphatase 22, 18.104.22.168, 22.214.171.124, JNK-stimulatory phosphatase-1, JSP-1, Low molecular weight dual specificity phosphatase 2, LMW-DSP2, Mitogen-activated protein kinase phosphatase x, MAP kinase phosphatase x, MKP-x, DUSP22, JSP1, LMWDSP2, MKPX|
|Target/Specificity||Human DUSP22. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||DUSP22 / JSP 1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||JSP1, LMWDSP2, MKPX|
|Function||Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N- terminal kinase (SAPK/JNK) (By similarity).|
|Cellular Location||Cytoplasm. Nucleus|
|Tissue Location||Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas|
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Provided below are standard protocols that you may find useful for product applications.
Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N- terminal kinase (SAPK/JNK) (By similarity).
Shen Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:13613-13618(2001).
Gu J.,et al.Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
Mao Y.,et al.Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
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