DUSP22 / JSP 1 Antibody (Internal)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | Q9NRW4 |
Reactivity | Human, Rabbit, Monkey, Horse, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 21kDa |
Dilution | IHC-P (4 µg/ml) |
Gene ID | 56940 |
---|---|
Other Names | Dual specificity protein phosphatase 22, 3.1.3.16, 3.1.3.48, JNK-stimulatory phosphatase-1, JSP-1, Low molecular weight dual specificity phosphatase 2, LMW-DSP2, Mitogen-activated protein kinase phosphatase x, MAP kinase phosphatase x, MKP-x, DUSP22, JSP1, LMWDSP2, MKPX |
Target/Specificity | Human DUSP22. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | DUSP22 / JSP 1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DUSP22 |
---|---|
Synonyms | JSP1, LMWDSP2, MKPX |
Function | Activates the Jnk signaling pathway. |
Cellular Location | Cytoplasm. |
Tissue Location | Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N- terminal kinase (SAPK/JNK) (By similarity).
References
Shen Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:13613-13618(2001).
Gu J.,et al.Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
Mao Y.,et al.Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
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