|Reactivity||Human, Rabbit, Horse, Bovine, Dog|
|Dilution||IHC-P (6.5 µg/ml)|
|Other Names||Cell division cycle 7-related protein kinase, CDC7-related kinase, HsCdc7, huCdc7, 188.8.131.52, CDC7, CDC7L1|
|Target/Specificity||Human CDC7. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||CDC7 Antibody (Kinase Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.|
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Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.
Sato N.,et al.EMBO J. 16:4340-4351(1997).
Hess G.F.,et al.Gene 211:133-140(1998).
Jiang W.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:14320-14325(1997).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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