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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ERP44 Antibody (Internal)   

ERP44 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IHC - ERP44 Antibody (Internal) ALS10958
    Anti-ERP44 / TXNDC4 antibody ALS10958 IHC of human stomach.
  • IHC - ERP44 Antibody (Internal) ALS10958
    Anti-ERP44 / TXNDC4 antibody ALS10958 IHC of human placenta.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q9BS26
Reactivity Human, Mouse, Rabbit, Monkey, Pig, Chicken, Horse, Xenopus, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 47kDa
Dilution IHC-P (15-20 µg/ml)
Additional Information
Gene ID 23071
Other Names Endoplasmic reticulum resident protein 44, ER protein 44, ERp44, Thioredoxin domain-containing protein 4, ERP44, KIAA0573, TXNDC4
Target/Specificity Human ERP44 / TXNDC4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsERP44 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ERP44
Synonyms KIAA0573, TXNDC4
Function Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum.
Cellular Location Endoplasmic reticulum lumen.
Volume 50 µl
Research Areas
Citations (0)

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Background

Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.

References

Anelli T.,et al.EMBO J. 21:835-844(2002).
Nagase T.,et al.DNA Res. 5:31-39(1998).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Humphray S.J.,et al.Nature 429:369-374(2004).

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$ 395.00
Cat# ALS10958
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