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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MFI2 / p97 Antibody (N-Terminus)   

MFI2 / p97 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - MFI2 / p97 Antibody (N-Terminus) ALS10974
    Anti-MFI2 antibody ALS10974 IHC of human breast.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P08582
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 80kDa
Dilution IHC-P (10-15 µg/ml)
Additional Information
Gene ID 4241
Other Names Melanotransferrin, Melanoma-associated antigen p97, CD228, MFI2, MAP97
Target/Specificity Human MFI2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsMFI2 / p97 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MELTF (HGNC:7037)
Synonyms MAP97, MFI2
Function Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.
Cellular Location Isoform 1: Cell membrane; Lipid-anchor, GPI- anchor
Tissue Location Found predominantly in human melanomas and in certain fetal tissues; also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts
Research Areas
Citations (0)

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Background

Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.

References

Rose T.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:1261-1265(1986).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Furukawa K.S.,et al.J. Exp. Med. 169:585-590(1989).
Food M.R.,et al.J. Biol. Chem. 269:3034-3040(1994).
Kennard M.L.,et al.EMBO J. 14:4178-4186(1995).

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$ 395.00
Cat# ALS10974
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