|Dilution||IHC-P (10-15 µg/ml)|
|Other Names||Melanotransferrin, Melanoma-associated antigen p97, CD228, MFI2, MAP97|
|Target/Specificity||Human MFI2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||MFI2 / p97 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.|
|Cellular Location||Isoform 1: Cell membrane; Lipid-anchor, GPI- anchor|
|Tissue Location||Found predominantly in human melanomas and in certain fetal tissues; also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts|
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Provided below are standard protocols that you may find useful for product applications.
Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.
Rose T.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:1261-1265(1986).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Furukawa K.S.,et al.J. Exp. Med. 169:585-590(1989).
Food M.R.,et al.J. Biol. Chem. 269:3034-3040(1994).
Kennard M.L.,et al.EMBO J. 14:4178-4186(1995).
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