|Dilution||IHC-P (10-15 µg/ml)|
|Other Names||Melanotransferrin, Melanoma-associated antigen p97, CD228, MFI2, MAP97|
|Target/Specificity||Human MFI2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||MFI2 / p97 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.|
|Cellular Location||Isoform 1: Cell membrane; Lipid-anchor, GPI- anchor|
|Tissue Location||Found predominantly in human melanomas and in certain fetal tissues; also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts|
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Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.
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Muzny D.M.,et al.Nature 440:1194-1198(2006).
Furukawa K.S.,et al.J. Exp. Med. 169:585-590(1989).
Food M.R.,et al.J. Biol. Chem. 269:3034-3040(1994).
Kennard M.L.,et al.EMBO J. 14:4178-4186(1995).
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