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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   CDCP1 Antibody (Extracellular Domain)   

CDCP1 Antibody (Extracellular Domain)

Rabbit Polyclonal Antibody

     
  • IHC - CDCP1 Antibody (Extracellular Domain) ALS10983
    Anti-CDCP1 antibody ALS10983 IHC of human prostate.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q9H5V8
Reactivity Human, Monkey, Horse
Host Rabbit
Clonality Polyclonal
Calculated MW 93kDa
Dilution IHC-P (10-12.5 µg/ml)
Additional Information
Gene ID 64866
Other Names CUB domain-containing protein 1, Membrane glycoprotein gp140, Subtractive immunization M plus HEp3-associated 135 kDa protein, SIMA135, Transmembrane and associated with src kinases, CD318, CDCP1, TRASK
Target/Specificity Human CDCP1. BLAST analysis of the peptide immunogen showed no homology with other human proteins. Immunogenic peptide is found in isoform 1 and 3.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsCDCP1 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDCP1
Synonyms TRASK
Function May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
Cellular Location Isoform 1: Cell membrane; Single-pass membrane protein. Note=Shedding may also lead to a soluble peptide
Tissue Location Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells
Volume 50 µl
Research Areas
Citations (0)

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Background

May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.

References

Scherl-Mostageer M.,et al.Oncogene 20:4402-4408(2001).
Hooper J.D.,et al.Oncogene 22:1783-1794(2003).
Bhatt A.S.,et al.Oncogene 24:5333-5343(2005).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS10983
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