BEST2 / Bestrophin-2 Antibody (Internal)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | Q8NFU1 |
Reactivity | Human, Monkey, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 57kDa |
Dilution | IHC-P (2.5-5 µg/ml) |
Gene ID | 54831 |
---|---|
Other Names | Bestrophin-2, Vitelliform macular dystrophy 2-like protein 1, BEST2, VMD2L1 |
Target/Specificity | Human BEST2 / Bestrophin-2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except BEST1 (47%). |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | BEST2 / Bestrophin-2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | BEST2 |
---|---|
Synonyms | VMD2L1 |
Function | Forms calcium-sensitive chloride channels. Permeable to bicarbonate. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Mainly confined to the retinal pigment epithelium and colon. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
References
Stoehr H.,et al.Eur. J. Hum. Genet. 10:281-284(2002).
Tsunenari T.,et al.J. Biol. Chem. 278:41114-41125(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Sun H.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:4008-4013(2002).
Qu Z.,et al.Am. J. Physiol. 294:C1371-C1377(2008).
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