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SLC12A2 / NKCC1 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - SLC12A2 / NKCC1 Antibody (N-Terminus) ALS11032
    Anti-SLC12A2 / NKCC1 antibody ALS11032 IHC of human prostate.
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  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P55011
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 131kDa
Dilution IHC-P (7.5-10 µg/ml)
Additional Information
Gene ID 6558
Other Names Solute carrier family 12 member 2, Basolateral Na-K-Cl symporter, Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1, SLC12A2, NKCC1
Target/Specificity Human SLC12A2 / NKCC1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsSLC12A2 / NKCC1 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC12A2
Function Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane (PubMed:32081947, PubMed:33597714, PubMed:32294086, PubMed:7629105, PubMed:16669787). Plays a vital role in the regulation of ionic balance and cell volume (PubMed:32081947, PubMed:32294086, PubMed:7629105, PubMed:16669787).
Cellular Location Basolateral cell membrane; Multi-pass membrane protein
Tissue Location Expressed in many tissues.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.

References

Payne J.A.,et al.J. Biol. Chem. 270:17977-17985(1995).
Vibat C.R.,et al.Anal. Biochem. 298:218-230(2001).
Cantin G.T.,et al.J. Proteome Res. 7:1346-1351(2008).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cruz-Rangel S.,et al.Am. J. Physiol. 301:C601-C608(2011).

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Discontinued
Cat# ALS11032
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