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NPTN / SDR1 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IHC - NPTN / SDR1 Antibody (Internal) ALS11049
    Anti-NPTN antibody ALS11049 IHC of human colon.
  • IHC - NPTN / SDR1 Antibody (Internal) ALS11049
    Anti-NPTN antibody ALS11049 IHC of human breast.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q9Y639
Reactivity Human, Mouse, Rabbit, Hamster, Monkey, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 44kDa
Dilution IHC-P (15-20 µg/ml)
Additional Information
Gene ID 27020
Other Names Neuroplastin, Stromal cell-derived receptor 1, SDR-1, NPTN, SDFR1, SDR1
Target/Specificity Human NPTN. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsNPTN / SDR1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NPTN
Synonyms SDFR1, SDR1
Function Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein. Note=Enriched at postsynaptic density.
Tissue Location Isoform 1 is ubiquitously expressed. Isoform 2 is expressed in brain cortex and cerebellum (at protein level) {ECO:0000269|PubMed:17196182, ECO:0000269|Ref.1}
Volume 100 µl
Research Areas
Citations (0)

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Background

Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity (By similarity).

References

Lopez N.D.,et al.Biomed. Res. 20:43-49(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).

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$ 395.00
Cat# ALS11049
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