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WNT10A Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IHC - WNT10A Antibody (Internal) ALS11062
    Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • IHC - WNT10A Antibody (Internal) ALS11062
    Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • IHC - WNT10A Antibody (Internal) ALS11062
    Anti-WNT10A antibody ALS11062 IHC of human pancreatic islet.
  • IHC - WNT10A Antibody (Internal) ALS11062
    Human Melanoma (Lymph Node): Formalin-Fixed, Paraffin-Embedded (FFPE)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q9GZT5
Reactivity Human, Mouse, Rabbit, Hamster, Monkey, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 46kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 80326
Other Names Protein Wnt-10a, WNT10A
Target/Specificity Human WNT10A. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsWNT10A Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WNT10A
Function Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). Plays a role in normal ectoderm development (PubMed:17847007, PubMed:28589954). Required for normal tooth development (PubMed:17847007, PubMed:29178643, PubMed:28589954). Required for normal postnatal development and maintenance of tongue papillae and sweat ducts (PubMed:28589954). Required for normal proliferation of basal cells in tongue filiform papillae, plantar epithelium and sweat ducts. Required for normal expression of keratins in tongue papillae (By similarity). Required for normal expression of KRT9 in foot plant epithelium (PubMed:28589954). Required for normal hair follicle function (PubMed:28589954).
Cellular Location Secreted, extracellular space, extracellular matrix. Secreted
Research Areas
Citations (0)

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Background

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters.

References

Testa T.T.,et al.Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
Rump A.,et al.Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
Kirikoshi H.,et al.Biochem. Biophys. Res. Commun. 283:798-805(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).

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$ 425.00
Cat# ALS11062
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