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WNT6 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IHC - WNT6 Antibody (Internal) ALS11066
    Anti-WNT6 antibody ALS11066 IHC of human breast, epithelium cells.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q9Y6F9
Reactivity Human, Rabbit, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 40kDa
Dilution IHC-P (20 µg/ml)
Additional Information
Gene ID 7475
Other Names Protein Wnt-6, WNT6
Target/Specificity Human WNT6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsWNT6 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WNT6
Function Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Expressed in gastric cancer cell lines and gastric cancer tissues (at protein level). Detected in the apical gland region of the gastric foveolar epithelium (at protein level).
Volume 50 µl
Research Areas
Citations (0)

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Background

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway.

References

Testa T.T.,et al.Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
Kirikoshi H.,et al.Biochem. Biophys. Res. Commun. 283:798-805(2001).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Rump A.,et al.Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
Rankin J.,et al.Cytogenet. Cell Genet. 84:50-52(1999).

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$ 395.00
Cat# ALS11066
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