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STEAP2 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IHC - STEAP2 Antibody (Internal) ALS11074
    Anti-STEAP2 antibody ALS11074 IHC of human uterus.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q8NFT2
Reactivity Human, Mouse, Rabbit, Hamster, Monkey, Horse, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 56kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 261729
Other Names Metalloreductase STEAP2, 1.16.1.-, Prostate cancer-associated protein 1, Protein up-regulated in metastatic prostate cancer, PUMPCn, Six-transmembrane epithelial antigen of prostate 2, SixTransMembrane protein of prostate 1, STEAP2, PCANAP1, STAMP1
Target/Specificity Human STEAP2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsSTEAP2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STEAP2
Synonyms PCANAP1, STAMP1
Function Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane (By similarity). Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate (By similarity). Can also reduce Cu(2+) to Cu(1+) (By similarity).
Cellular Location Endosome membrane {ECO:0000250|UniProtKB:Q8BWB6}; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Tissue Location Expressed at high levels in prostate and at significantly lower levels in heart, brain, kidney, pancreas, and ovary.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).

References

Korkmaz K.S.,et al.J. Biol. Chem. 277:36689-36696(2002).
Porkka K.P.,et al.Lab. Invest. 82:1573-1582(2002).
Zhang Z.,et al.Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Hillier L.W.,et al.Nature 424:157-164(2003).

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Discontinued
Cat# ALS11074
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