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GCNT3 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IHC - GCNT3 Antibody (Internal) ALS11096
    Anti-GCNT3 antibody ALS11096 IHC of human stomach.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession O95395
Reactivity Human, Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 51kDa
Dilution IHC-P (5-7.5 µg/ml)
Additional Information
Gene ID 9245
Other Names Beta-1, 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase 3, 2.4.1.102, 2.4.1.150, C2GnT-mucin type, C2GnT-M, hC2GnT-M, Core 2/core 4 beta-1, 6-N-acetylglucosaminyltransferase, C2/4GnT, GCNT3
Target/Specificity Human GCNT3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsGCNT3 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GCNT3
Function Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.
Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location Primarily expressed in mucus-secreting tissues. Expressed in colon, kidney, small intestine, trachea, and stomach, where mucin is produced.
Volume 50 µl
Research Areas
Citations (0)

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Background

Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.

References

Yeh J.-C.,et al.J. Biol. Chem. 274:3215-3221(1999).
Schwientek T.,et al.J. Biol. Chem. 274:4504-4512(1999).
Tan S.,et al.Am. J. Respir. Cell Mol. Biol. 36:737-745(2007).
Ishibashi Y.,et al.Glycoconj. J. 22:53-62(2005).
Huang M.-C.,et al.Oncogene 25:3267-3276(2006).

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$ 395.00
Cat# ALS11096
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