|Dilution||IHC-P (10-20 µg/ml)|
|Other Names||Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150, 95 alpha chain, Leukocyte adhesion receptor p150, 95, CD11c, ITGAX, CD11C|
|Target/Specificity||Human CD11c. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||ITGAX / CD11c Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Predominantly expressed in monocytes and granulocytes|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Corbi A.L.,et al.EMBO J. 6:4023-4028(1987).
Corbi A.L.,et al.J. Biol. Chem. 265:2782-2788(1990).
Corbi A.L.,et al.J. Biol. Chem. 265:12750-12751(1990).
Miller L.J.,et al.J. Immunol. 138:2381-2383(1987).
Chen R.,et al.J. Proteome Res. 8:651-661(2009).
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