|Dilution||IHC-P (10-20 µg/ml)|
|Other Names||Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150, 95 alpha chain, Leukocyte adhesion receptor p150, 95, CD11c, ITGAX, CD11C|
|Target/Specificity||Human CD11c. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||ITGAX / CD11c Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Predominantly expressed in monocytes and granulocytes|
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Provided below are standard protocols that you may find useful for product applications.
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Corbi A.L.,et al.EMBO J. 6:4023-4028(1987).
Corbi A.L.,et al.J. Biol. Chem. 265:2782-2788(1990).
Corbi A.L.,et al.J. Biol. Chem. 265:12750-12751(1990).
Miller L.J.,et al.J. Immunol. 138:2381-2383(1987).
Chen R.,et al.J. Proteome Res. 8:651-661(2009).
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