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SLC1A3 / EAAT1 Antibody (Cytoplasmic Domain)

Rabbit Polyclonal Antibody

     
  • IHC - SLC1A3 / EAAT1 Antibody (Cytoplasmic Domain) ALS11109
    Anti-SLC1A3 / GLAST antibody ALS11109 IHC of human brain, cerebellum, molecular layer and...
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P43003
Reactivity Human, Monkey
Host Rabbit
Clonality Polyclonal
Calculated MW 60kDa
Dilution IHC-P (2.5 µg/ml)
Additional Information
Gene ID 6507
Other Names Excitatory amino acid transporter 1, Sodium-dependent glutamate/aspartate transporter 1, GLAST-1, Solute carrier family 1 member 3, SLC1A3, EAAT1, GLAST, GLAST1
Target/Specificity Human SLC1A3 / GLAST. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsSLC1A3 / EAAT1 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC1A3
Synonyms EAAT1, GLAST, GLAST1
Function Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia
Research Areas
Citations (0)

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Background

Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.

References

Shashidharan P.,et al.Biochim. Biophys. Acta 1216:161-164(1993).
Arriza J.L.,et al.J. Neurosci. 14:5559-5569(1994).
Kawakami H.,et al.Biochem. Biophys. Res. Commun. 199:171-176(1994).
Stoffel W.,et al.FEBS Lett. 386:189-193(1996).
Vallejo-Illarramendi A.,et al.J. Neurochem. 95:341-348(2005).

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$ 395.00
Cat# ALS11109
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