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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   ESYT1 Antibody (C-Terminus)   

ESYT1 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - ESYT1 Antibody (C-Terminus) ALS11122
    Anti-ESYT1 / FAM62A antibody ALS11122 IHC of human small intestine.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q9BSJ8
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 123kDa
Dilution IHC-P (10-12.5 µg/ml)
Additional Information
Gene ID 23344
Other Names Extended synaptotagmin-1, E-Syt1, Membrane-bound C2 domain-containing protein, ESYT1, FAM62A, KIAA0747, MBC2
Target/Specificity Human ESYT1 / FAM62A. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsESYT1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ESYT1
Synonyms FAM62A, KIAA0747, MBC2
Function Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Peripheral membrane protein Note=Localizes primarily to the endoplasmic reticulum. Recruited to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels
Tissue Location Widely expressed.
Volume 50 µl
Research Areas
Citations (0)

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Background

Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane.

References

Min S.-W.,et al.Proc. Natl. Acad. Sci. U.S.A. 104:3823-3828(2007).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Nagase T.,et al.DNA Res. 5:277-286(1998).
Bienvenut W.V.,et al.Submitted (NOV-2005) to UniProtKB.

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$ 395.00
Cat# ALS11122
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