|Reactivity||Human, Mouse, Hamster|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Protein Wnt-16, WNT16|
|Target/Specificity||Human WNT16. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CETN3 (50%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||WNT16 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
|Tissue Location||Isoform Wnt-16b is expressed in peripheral lymphoid organs such as spleen, appendix, and lymph nodes, in kidney but not in bone marrow. Isoform Wnt-16a is expressed at significant levels only in the pancreas|
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Provided below are standard protocols that you may find useful for product applications.
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).
McWhirter J.R.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:11464-11469(1999).
Fear M.W.,et al.Biochem. Biophys. Res. Commun. 278:814-820(2000).
Hillier L.W.,et al.Nature 424:157-164(2003).
Sjoeblom T.,et al.Science 314:268-274(2006).
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