|Reactivity||Human, Mouse, Hamster|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Protein Wnt-16, WNT16|
|Target/Specificity||Human WNT16. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CETN3 (50%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||WNT16 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
|Tissue Location||Isoform Wnt-16b is expressed in peripheral lymphoid organs such as spleen, appendix, and lymph nodes, in kidney but not in bone marrow. Isoform Wnt-16a is expressed at significant levels only in the pancreas|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).
McWhirter J.R.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:11464-11469(1999).
Fear M.W.,et al.Biochem. Biophys. Res. Commun. 278:814-820(2000).
Hillier L.W.,et al.Nature 424:157-164(2003).
Sjoeblom T.,et al.Science 314:268-274(2006).
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