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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   COMT Antibody (Internal)   

COMT Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IHC - COMT Antibody (Internal) ALS11168
    Anti-COMT antibody ALS11168 IHC of human brain, cerebellum.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P21964
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 30kDa
Dilution IHC-P (10-15 µg/ml)
Additional Information
Gene ID 1312
Other Names Catechol O-methyltransferase, 2.1.1.6, COMT
Target/Specificity Human COMT. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsCOMT Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name COMT
Function Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
Cellular Location Isoform Soluble: Cytoplasm.
Tissue Location Brain, liver, placenta, lymphocytes and erythrocytes
Volume 50 µl
Research Areas
Citations (0)

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Background

Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.

References

Lundstroem K.,et al.DNA Cell Biol. 10:181-189(1991).
Bertocci B.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:1416-1420(1991).
Tenhunen J.,et al.Eur. J. Biochem. 223:1049-1059(1994).
Li J.Y.,et al.Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS11168
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