REEP5 Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | Q00765 |
Reactivity | Human, Mouse, Monkey |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 21kDa |
Dilution | IHC-P (2.5 µg/ml) |
Gene ID | 7905 |
---|---|
Other Names | Receptor expression-enhancing protein 5, Polyposis locus protein 1, Protein TB2, REEP5, C5orf18, DP1, TB2 |
Target/Specificity | Human REEP5. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | REEP5 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | REEP5 |
---|---|
Synonyms | C5orf18, DP1, TB2 |
Function | Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes. |
Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q60870}; Multi-pass membrane protein. Note=Localizes to endoplasmic reticulum tubular network (PubMed:23969831). In cardiomyocytes, localizes to the junctional sarcoplasmic reticulum membrane which is closely tethered to the cell membrane and contractile machinery (By similarity) {ECO:0000250|UniProtKB:Q60870, ECO:0000269|PubMed:23969831} |
Tissue Location | Expressed in heart (at protein level) (PubMed:32075961). Expressed in circumvallate papillae and testis (PubMed:16720576). |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
May promote functional cell surface expression of olfactory receptors.
References
Joslyn G.,et al.Cell 66:601-613(1991).
Kinzler K.W.,et al.Science 253:661-665(1991).
Saito H.,et al.Cell 119:679-691(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).
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