|Dilution||IHC-P (5-10 µg/ml)|
|Other Names||Ghrelin O-acyltransferase, 2.3.1.-, Membrane-bound O-acyltransferase domain-containing protein 4, O-acyltransferase domain-containing protein 4, MBOAT4, GOAT, OACT4|
|Target/Specificity||Human MBOAT4. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except METTL10 (57%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||FKSG89 / MBOAT4 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Mediates the octanoylation of ghrelin at 'Ser-3'. Can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic acid.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
|Tissue Location||Expressed predominantly in stomach with moderate levels in pancreas and relatively low levels in most other tissues.|
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Mediates the octanoylation of ghrelin at 'Ser-3'. Can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic acid.
Gutierrez J.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:6320-6325(2008).
Wang Y.-G.,et al.Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
Nusbaum C.,et al.Nature 439:331-335(2006).
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