|Reactivity||Human, Mouse, Monkey, Pig, Horse, Bovine, Guinea Pig|
|Dilution||IHC-P (2.5-5 µg/ml)|
|Other Names||Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1, 220.127.116.11, D-fructose-6-phosphate amidotransferase 1, Glutamine:fructose-6-phosphate amidotransferase 1, GFAT 1, GFAT1, Hexosephosphate aminotransferase 1, GFPT1, GFAT, GFPT|
|Target/Specificity||Human GFPT1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||GFPT1 / GFAT Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes ARNTL/BMAL1 and CRY1.|
|Tissue Location||Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes ARNTL/BMAL1 and CRY1.
McKnight G.L.,et al.J. Biol. Chem. 267:25208-25212(1992).
Hillier L.W.,et al.Nature 434:724-731(2005).
DeHaven J.E.,et al.Diabetes 50:2419-2424(2001).
Olsen J.V.,et al.Cell 127:635-648(2006).
Beausoleil S.A.,et al.Nat. Biotechnol. 24:1285-1292(2006).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.