|Application ||WB, IHC-P, IP, IHC-Fr|
|Reactivity||Human, Mouse, Rat, Monkey|
|Dilution||IHC-P (10-20 µg/ml)|
|Other Names||Solute carrier family 2, facilitated glucose transporter member 4, Glucose transporter type 4, insulin-responsive, GLUT-4, SLC2A4, GLUT4|
|Target/Specificity||Recognizes glucose transporter 4 (GLUT4). It does not react with HEP G2 type glucose transporter in human erythrocytes, rat brain or other tissues that do not exhibit sensitivity to insulin.|
|Reconstitution & Storage||+4°C or -20°C, Avoid repeated freezing and thawing.|
|Precautions||SLC2A4 / GLUT-4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Insulin-regulated facilitative glucose transporter.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region. Note=Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized. The dileucine internalization motif is critical for intracellular sequestration|
|Tissue Location||Skeletal and cardiac muscles; brown and white fat|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Insulin-regulated facilitative glucose transporter.
Fukumoto H.,et al.J. Biol. Chem. 264:7776-7779(1989).
Buse J.B.,et al.Diabetes 41:1436-1445(1992).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Chiaramonte R.,et al.Gene 130:307-308(1993).
Verhey K.J.,et al.J. Biol. Chem. 269:2353-2356(1994).
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