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ROBO1 Antibody (aa1632-1644)

Rabbit Polyclonal Antibody

     
  • IHC - ROBO1 Antibody (aa1632-1644) ALS11243
    Anti-ROBO1 antibody IHC of human brain.
  • IF - ROBO1 Antibody (aa1632-1644) ALS11243
    Immunofluorescence - Anti-ROBO-1 Antibody.
  • IF - ROBO1 Antibody (aa1632-1644) ALS11243
    Immunofluorescence - Anti-ROBO-1 Antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, ICC, E
Primary Accession Q9Y6N7
Reactivity Human, Mouse, Rat, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 181kDa
Dilution ELISA (1:30000-1:160000), IHC-P (2.5 µg/ml), WB (1:500-1:3000)
Additional Information
Gene ID 6091
Other Names Roundabout homolog 1, Deleted in U twenty twenty, H-Robo-1, ROBO1, DUTT1
Target/Specificity Amino acids 1632-1644 of Human ROBO-1.
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsROBO1 Antibody (aa1632-1644) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ROBO1
Synonyms DUTT1
Function Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Widely expressed, with exception of kidney.
Research Areas
Citations (0)

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Background

Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development.

References

Kidd T.,et al.Cell 92:205-215(1998).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Brose K.,et al.Cell 96:795-806(1999).

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$ 395.00
Cat# ALS11243
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(40 western blots)
Availability: 5 days
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