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GNAS Antibody (aa385-394)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, E |
|---|---|
| Primary Accession | P84996 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 68kDa |
| Dilution | ELISA (1:1000), IHC-P (20 µg/ml), |
| Gene ID | 2778 |
|---|---|
| Other Names | Protein ALEX, Alternative gene product encoded by XL-exon, GNAS (HGNC:4392) |
| Target/Specificity | Amino acids 385 to 394 of human GNAS |
| Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
| Precautions | GNAS Antibody (aa385-394) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GNAS (HGNC:4392) |
|---|---|
| Function | May inhibit the adenylyl cyclase-stimulating activity of guanine nucleotide-binding protein G(s) subunit alpha which is produced from the same locus in a different open reading frame. |
| Cellular Location | Cell membrane; Peripheral membrane protein. Cell projection, ruffle. Note=Predominantly associated with cell membrane ruffles. |
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Provided below are standard protocols that you may find useful for product applications.
Background
May inhibit the adenylyl cyclase-stimulating activity of guanine nucleotide-binding protein G(s) subunit alpha which is produced from the same locus in a different open reading frame.
References
Deloukas P.,et al.Nature 414:865-871(2001).
Freson K.,et al.Hum. Mol. Genet. 12:1121-1130(2003).
Abramowitz J.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:8366-8371(2004).
Liu J.,et al.J. Clin. Invest. 106:1167-1174(2000).
Bastepe M.,et al.Am. J. Hum. Genet. 68:1283-1289(2001).
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