|Application ||IHC-P, E|
|Dilution||ELISA (1:1000), IHC-P (2.5 µg/ml),|
|Other Names||Low-density lipoprotein receptor-related protein 2, LRP-2, Glycoprotein 330, gp330, Megalin, LRP2|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||LRP2 / Megalin Antibody (aa4641-4655) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts together with cubilin to mediate HDL endocytosis (By similarity). May participate in regulation of parathyroid- hormone and para-thyroid-hormone-related protein release.|
|Cellular Location||Membrane; Single-pass type I membrane protein. Membrane, coated pit|
|Tissue Location||Absorptive epithelia, including renal proximal tubules|
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Provided below are standard protocols that you may find useful for product applications.
Acts together with cubilin to mediate HDL endocytosis (By similarity). May participate in regulation of parathyroid- hormone and para-thyroid-hormone-related protein release.
Hjaelm G.,et al.Eur. J. Biochem. 239:132-137(1996).
Hillier L.W.,et al.Nature 434:724-731(2005).
Korenberg J.R.,et al.Genomics 22:88-93(1994).
Lundgren S.,et al.Exp. Cell Res. 212:344-350(1994).
Kounnas M.Z.,et al.J. Biol. Chem. 270:13070-13075(1995).
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