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REN / Renin 1 Antibody

Sheep Polyclonal Antibody

     
  • IHC - REN / Renin 1 Antibody ALS11270
    Anti-REN / Renin antibody IHC of human kidney.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P00797
Reactivity Human
Host Sheep
Clonality Polyclonal
Calculated MW 45kDa
Dilution IHC-P (2.5 µg/ml)
Additional Information
Gene ID 5972
Other Names Renin, 3.4.23.15, Angiotensinogenase, REN
Target/Specificity Human renin
Reconstitution & Storage Store at -70°C, avoid freeze/thaw cycles.
PrecautionsREN / Renin 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name REN
Function Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
Cellular Location Secreted. Membrane. Note=Associated to membranes via binding to ATP6AP2.
Research Areas
Citations (0)
citation

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Background

Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.

References

Imai T.,et al.Proc. Natl. Acad. Sci. U.S.A. 80:7405-7409(1983).
Morris B.J.,et al.Clin. Sci. 71:345-355(1986).
Hardman J.A.,et al.DNA 3:457-468(1984).
Rieder M.J.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

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Discontinued
Cat# ALS11270
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