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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TRPC3 Antibody (C-Terminus)   

TRPC3 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - TRPC3 Antibody (C-Terminus) ALS11278
    Immunofluorescence of TRPC3 in Mouse Heart cells with TRPC3 antibody at 20 ug/ml.
  • WB - TRPC3 Antibody (C-Terminus) ALS11278
    Western blot of TRPC3 in human brain tissue lysate with TRPC3 antibody at (A) 1 and (B) 2 ug/ml.
  • IHC - TRPC3 Antibody (C-Terminus) ALS11278
    Anti-TRPC3 antibody IHC of human skeletal muscle.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession Q13507
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 96kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 7222
Other Names Short transient receptor potential channel 3, TrpC3, Transient receptor protein 3, TRP-3, hTrp-3, hTrp3, TRPC3, TRP3
Target/Specificity 14 amino acid peptide from near the carboxy terminus of human TRPC3
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsTRPC3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRPC3
Synonyms TRP3
Function Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol 1,4,5- triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Expressed predominantly in brain and at much lower levels in ovary, colon, small intestine, lung, prostate, placenta and testis
Research Areas
Citations (0)

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Background

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol 1,4,5- triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion.

References

Zhu X.,et al.Cell 85:661-671(1996).
Xu X.-Z.S.,et al.Cell 89:1155-1164(1997).
Yildirim E.,et al.Proc. Natl. Acad. Sci. U.S.A. 102:3307-3311(2005).
Yamazaki D.,et al.Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).

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$ 395.00
Cat# ALS11278
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