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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   ANAPC10 / APC10 Antibody (aa10-20)   

ANAPC10 / APC10 Antibody (aa10-20)

Rabbit Polyclonal Antibody

     
  • IHC - ANAPC10 / APC10 Antibody (aa10-20) ALS11299
    Anti-ANAPC10 / APC10 antibody IHC of human pancreas.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9UM13
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 21kDa
Dilution IHC-P (2.5 µg/ml)
Additional Information
Gene ID 10393
Other Names Anaphase-promoting complex subunit 10, APC10, Cyclosome subunit 10, ANAPC10, APC10
Target/Specificity aa 10-20 of Human APC10 (Anaphase-promoting complex or cyclosome).
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsANAPC10 / APC10 Antibody (aa10-20) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ANAPC10
Synonyms APC10
Function Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Volume 50 µl
Research Areas
Citations (0)

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Background

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

References

Grossberger R.,et al.J. Biol. Chem. 274:14500-14507(1999).
Kurasawa Y.,et al.Oncogene 18:5131-5137(1999).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Jin L.,et al.Cell 133:653-665(2008).

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$ 395.00
Cat# ALS11299
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