|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:2000-1:10000), IHC-P (5 µg/ml), WB (1:500-1:3000)|
|Other Names||Cyclin-L2, Paneth cell-enhanced expression protein, CCNL2|
|Target/Specificity||Synthetic polypeptide corresponding to amino acids 309-384 of Human Cyclin L2a protein.|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.|
|Precautions||CCNL2 / Cyclin L2 Antibody (aa309-384) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in pre-mRNA splicing. May induce cell death, possibly by acting on the transcription and RNA processing of apoptosis-related factors.|
|Cellular Location||Nucleus speckle Nucleus, nucleoplasm|
|Tissue Location||Widely expressed.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Also modulates the expression of critical apoptotic factor, leading to cell apoptosis.
Yang L.,et al.J. Biol. Chem. 279:11639-11648(2004).
Jikuya H.,et al.Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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