|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:2000-1:10000), IHC-P (5 µg/ml), WB (1:500-1:3000)|
|Other Names||Cyclin-L2, Paneth cell-enhanced expression protein, CCNL2|
|Target/Specificity||Synthetic polypeptide corresponding to amino acids 309-384 of Human Cyclin L2a protein.|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.|
|Precautions||CCNL2 / Cyclin L2 Antibody (aa309-384) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in pre-mRNA splicing. May induce cell death, possibly by acting on the transcription and RNA processing of apoptosis-related factors.|
|Cellular Location||Nucleus speckle Nucleus, nucleoplasm|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Also modulates the expression of critical apoptotic factor, leading to cell apoptosis.
Yang L.,et al.J. Biol. Chem. 279:11639-11648(2004).
Jikuya H.,et al.Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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