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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   EMI2 / FBXO43 Antibody (N-Terminus)   

EMI2 / FBXO43 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - EMI2 / FBXO43 Antibody (N-Terminus) ALS11325
    Anti-FBXO43 / EMI2 antibody IHC of human liver.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q4G163
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 78kDa
Dilution ELISA (1:10000-1:50000), IHC-P (2.5 µg/ml), WB (1:500-1:3000)
Additional Information
Gene ID 286151
Other Names F-box only protein 43, Endogenous meiotic inhibitor 2, FBXO43, EMI2
Target/Specificity A region approximately 60 residues downstream of the amino terminal end of human Fbp5B protein.
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsEMI2 / FBXO43 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FBXO43
Synonyms EMI2
Function Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation (Probable).
Research Areas
Citations (0)

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Background

Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation (Probable).

References

Nusbaum C.,et al.Nature 439:331-335(2006).
Jin J.,et al.Genes Dev. 18:2573-2580(2004).
Tung J.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 102:4318-4323(2005).
Hansen D.V.,et al.Proc. Natl. Acad. Sci. U.S.A. 103:608-613(2006).

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$ 395.00
Cat# ALS11325
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