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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GGA2 Antibody (aa249-265)   

GGA2 Antibody (aa249-265)

Rabbit Polyclonal Antibody

     
  • IHC - GGA2 Antibody (aa249-265) ALS11327
    Anti-GGA2 antibody IHC of human kidney.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q9UJY4
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 67kDa
Dilution IHC-P (2.5 µg/ml)
Additional Information
Gene ID 23062
Other Names ADP-ribosylation factor-binding protein GGA2, Gamma-adaptin-related protein 2, Golgi-localized, gamma ear-containing, ARF-binding protein 2, VHS domain and ear domain of gamma-adaptin, Vear, GGA2, KIAA1080
Target/Specificity Amino acids 249-265 of Human GGA2. This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Go ...
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsGGA2 Antibody (aa249-265) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GGA2
Synonyms KIAA1080
Function Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.
Cellular Location Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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Background

Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.

References

Boman A.L.,et al.Mol. Biol. Cell 11:1241-1255(2000).
Hirst J.,et al.J. Cell Biol. 149:67-80(2000).
Poussu A.,et al.J. Biol. Chem. 275:7176-7183(2000).
Loftus B.J.,et al.Genomics 60:295-308(1999).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS11327
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