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>   home   >   Products   >   Primary Antibodies   >   Microbiology   >   TLR8 Antibody (Internal)   

TLR8 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • WB - TLR8 Antibody (Internal) ALS11364
    Western blot of Rabbit Anti-TLR8 Antibody.
  • IHC - TLR8 Antibody (Internal) ALS11364
    Anti-TLR8 antibody IHC of human lung, alveolar macrophages.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q9NR97
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 120kDa
Dilution IHC-P (5 µg/ml), WB (1:500-1:2000),
Additional Information
Gene ID 51311
Other Names Toll-like receptor 8, CD288, TLR8
Target/Specificity An internal region of human TLR8 protein.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsTLR8 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TLR8
Function Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Detected in brain, heart, lung, liver, placenta, in monocytes, and at lower levels in CD11c+ immature dendritic cells
Research Areas
Citations (0)

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Background

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

References

Du X.,et al.Eur. Cytokine Netw. 11:362-371(2000).
Chuang T.-H.,et al.Eur. Cytokine Netw. 11:372-378(2000).
Nakajima T.,et al.Immunogenetics 60:727-735(2008).
Georgel P.,et al.PLoS ONE 4:E7803-E7803(2009).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).

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$ 395.00
Cat# ALS11364
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