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WRNIP1 / WHIP Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IHC - WRNIP1 / WHIP Antibody (Internal) ALS11369
    Anti-WRNIP1 / WHIP antibody IHC of human kidney.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q96S55
Reactivity Human, Mouse, Rat, Monkey
Host Rabbit
Clonality Polyclonal
Calculated MW 72kDa
Dilution ELISA (1:10000-1:40000), IHC-P (2.5 µg/ml), WB (1:500-1:2000)
Additional Information
Gene ID 56897
Other Names ATPase WRNIP1, 3.6.1.3, Werner helicase-interacting protein 1, WRNIP1 (HGNC:20876)
Target/Specificity An internal region of the WHIP1 protein. The immunogen sequence shows 100% homology to human WHIP1 (isoform 1) and WHIP2 (isoform 2) with predicted molecular weights of 72.2 kD and 69.5 kD, respectively. The immunogen sequence also shows 100% homolog ...
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsWRNIP1 / WHIP Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WRNIP1 (HGNC:20876)
Function Functions as a modulator of initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased.
Cellular Location Nucleus. Note=Colocalizes with WRN in granular structures in the nucleus.
Tissue Location Ubiquitously expressed.
Citations (0)

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Background

Functions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. Has an intrinsic ATPase activity that functions as a sensor of DNA damage or of arrested replication forks and regulates the extent of DNA synthesis.

References

Kawabe Y.,et al.J. Biol. Chem. 276:20364-20369(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS11369
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