|Application ||WB, IHC-P, IF, ICC|
|Dilution||IHC-P (5 µg/ml)|
|Other Names||Bcl-2-interacting killer, Apoptosis inducer NBK, BIP1, BP4, BIK, NBK|
|Target/Specificity||15 amino acid peptide from near the amino terminus of human BIK|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||BIK Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.|
|Cellular Location||Endomembrane system; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Note=Around the nuclear envelope, and in cytoplasmic membranes|
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Provided below are standard protocols that you may find useful for product applications.
Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.
Boyd J.M.,et al.Oncogene 11:1921-1928(1995).
Han J.,et al.Mol. Cell. Biol. 16:5857-5864(1996).
Pun K.-T.,et al.Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases.
Castells A.,et al.Gastroenterology 117:831-837(1999).
Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
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